Health Benefits of Sappan Wood
Posted August 14, 2009on:
Decoction of wood and bark used for tuberculosis, diarrhea, dysentery, postpartum tonic, skin infections. and anemia.
Seeds used for stomach aches and nervous disorders.
Decoction of wood used postpartum as tonic.
Chiefly used as a dyewood, popular for coloring native fabrics.
In some parts of the Quezon province, a popular colorant for the coconut liquer, lambanog.
• Antimicrobial: Aqueous extract study showed antimicrobial activity against methicillin-sensitive S aureus (MSSA) as well MRSA and suggests a potential to restore the effectiveness of B-lactam antibiotics against MRSA..
• Immunosuppressive compenent: Brazilein, an important immunosuppressive component of CS showed inhibition of T cell proliferation and suppress mice humoral immune response.
• Antioxidant:Study results showed significant antioxidant activities of Caesalpinia sappan heartwood extracts.
• Anticonvulsant:Study of aqueous MeOH extracts isolated pure compounds sappanchalcone and brazilin which showed remarkable anticonvulsant activity.
• Xanthine Oxidase Inhibitors:Study of MeOH extract of Vietnamese CS isolated neoprotosappanin and protosappanin A dimethyl acetal which showed xanthine oxidase inhibitory activity comparable to allopurinol.
• Anti-allergic:Study of extracts of CS showed potent inhibitory activity against B-hexosaminidase release as marker of degranulation in rat basophilic leukemic cells. Among the compounds tested, sappanchalcone showed the most potent anti-allergic effect.
• Cardioactive effects of Brazilein:Brazilein obtained from CS ethanol extracts showed a positive inotropic action with little effect on heart rate and coronary perfusion, an effect achieved through inhibition of Na-K-ATPase system.
Additional Sources and Suggested Readings
(2) Brazilein, an important immunosuppressive component from Caesalpinia sappan L. / International Immunopharmacology
Vol 6, Issue 3, March 2006, Pages 426-432 / doi:10.1016/j.intimp.2005.09.012
(3) Antioxidant Activity of Caesalpinia sappan Heartwood / Biological & Pharmaceutical Bulletin Vol. 26 (2003) , No. 11 1534
(4) Anticonvulsant compounds from the wood of Caesalpinia sappan L. / Archives of Pharmacal Research. Vol 23, Number 4 / August, 2000 / DOI 10.1007/BF02975445
(5) Xanthine Oxidase Inhibitors from the Heartwood of Vietnamese Caesalpinia sappan / CHEMICAL & PHARMACEUTICAL BULLETIN
Vol. 53 (2005) , No. 8 984
(6) Anti-allergic activity of principles from the roots and heartwood of caesalpinia sappan on antigen-induced -hexosaminidase release / Phytotherapy Research
(7) Study on Cardioactive Effects of Brazilein /
“Caesalpinia sappan, known as Sibukaw Tree, treats hepatitis problems. It also includes diabetes.”